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May 24, 2006
Awakened?
As some have said over and over again..when it comes to the human mind...you just never know.
A drug commonly used as a sleeping pill appears to have had a miraculous effect on brain-damaged patients who have been in a permanent vegetative state for years, arousing them to the point where some are able to speak to their families, scientists report today.
The dramatic improvement occurs within 20 minutes of taking the drug, Zolpidem, and wears off after around four hours - at which point the patients return to their permanent vegetative state, according to a paper published in the medical journal NeuroRehabilitation.
According to Wesley Smith, the drug is Ambien:
This definitely needs to be researched and after proper vetting, put into appropriate clinical trials. It also illustrates that we really don't know what is going on inside the minds of people diagnosed as permanently unconscious. Moreover, if this is real--and it sure appears that it is--it should give us great pause before pulling the tube feeding of people diagnosed as PVS. The doctors involved also claimed that the drug could have wider application, hoping that "the drug could have uses in all kinds of brain damage, including Parkinson's disease and Alzheimer's."
Go check out Smith's blog for more bioethics news - on more "futile care" cases brewing in Texas and a link to an article by Will Saletan last week in Slate (gee how did I miss that...) about our "gentle descent into eugenics"
We've just taken another step down the slippery slope toward eugenics.
The step involves "preimplantation genetic diagnosis," in which clinics take sperm and eggs, make embryos in lab dishes, and screen them for genetic flaws. Embryos without flaws are implanted in the mother's womb. Those with flaws are frozen or discarded.
The Human Fertilization and Embryology Authority regulates PGD in Britain. Previously, it had approved PGD only to weed out genes that were nearly certain to cause a grave childhood disease or were certain to cause a grave adult disease. Last week, the HFEA stepped across that line. You can now chuck embryos in Britain for diseases that are more treatable, less likely to strike early in life, and less likely ever to occur in the person whom the embryo would become.
And in some good news..Stephen Hand updates (as of 5/17) us on the condition of his son Jeremy:
The nurse, Paula, and I were delighted, despite the fact that our Lazarus's first words since his anoxia-coma amounted to two words: "it hurts," as he was being hoyered from a chair back into his bed. He has been laughing at jokes, attentive and responsive to questions when he has the strength, nodding yes or no, and has two very strong handshakes when his hands are clasped. Speech therapy begins immediately. Today he is alert, moves his head off the pillow and easily to the right and left, sometimes appears worried, responsive in many ways. He is not able to move his legs yet and his hands only a little (despite that very strong handshake). People can think what they want, but we cannot but thank the Lord through the prayers of St. Walburga and John Paul II. The process continues. The neurologists at Saints Memorial, Lowell, in good faith, gave him no realistic hope and urged us to withdraw all life support, based on a CAT Scan and time lapse in coma, as you may recall. It is all in the record.
Posted by Amy Welborn | Permalink
Comments
Gattaca, here we come. Hooray for science!
:(
Pedantic Classicist
Posted by: APC at May 24, 2006 3:19:22 PM
This is just wonderful news! As the sister of a brother who was severely brain-damaged by encephalitis and died five years later, I know that we lived for this type of potential miracle. My brother was written off as that horrible word that describes carrots and onions out in the garden, but in the month before he died he suddenly started moving his left hand on command and crying again. I will forever be convinced that the pain he was feeling from an ulcer that was about to burst somehow triggered a chemical reaction in his body that brought him around. If we can just keep people in this state comfortable, fed and hydrated, and provide them with physical therapy so they don't stiffen up like poor Terri Schiavo, who knows what science will figure out to bring them back to us.
Speaking of which, I was so glad to read recently that Jeremy Hand, who some doctors said was hopelessly brain-damaged, is now responding more than could be imagined...except for those who believe in the power of prayer. Praise God.
Posted by: Dee at May 24, 2006 3:22:17 PM
The dramatic improvement occurs within 20 minutes of taking the drug, Zolpidem, and wears off after around four hours - at which point the patients return to their permanent vegetative state ....
I guess we need a new definition of 'permanent'.
Posted by: Alfredo at May 24, 2006 3:53:32 PM
An abstract of the Zolpidem research article can be found here:
http://iospress.metapress.com/(khqwrb55rktpei451clcvt55)/app/home/contribution.asp?referrer=parent&backto=issue,4,11;journal,1,33;linkingpublicationresults,1:103177,1
Posted by: Chip at May 24, 2006 4:07:48 PM
Shortcut to that abstract:
http://iospress.metapress.com/link.asp?id=1l4bx0xnxrl98f08
Posted by: Chip at May 24, 2006 4:12:58 PM
I just had to come back and comment on another story I read about this research:
“For every damaged area of the brain, there is a dormant area, which seems to be a sort of protective mechanism. The damaged tissue is dead, there’s nothing you can do,” he explained. “But it’s the dormant areas which ‘wake up’,” per scientist, Dr. Ralf Clauss.
http://www.lifesite.net/ldn/2006/may/06052401.html
I just had a good cry all these 29 years later. My brother had a CAT scan 6 months after his brain was damaged by the virus and the doctors told us it was severely scarred and "Jimmy" was gone forever. We never believed that and always treated him as though he was understanding everything we said, just not able to communicate. To think that the essence of that sweet little boy was just lying dormant waiting to be unlocked...it just leaves me heartbroken that we couldn't wake him up in time. My only comfort is, to paraphrase Job, "The Lord gave him to us and the Lord took him away...Blessed be the name of the Lord."
Posted by: Dee at May 24, 2006 4:41:25 PM
This story reminds me of one in which John Hardon, as a young priest, enrolled a brain damaged young boy in the Confraternity of the Miraculous Medal. During his prayers, the boy was miraculously cured.
I'm not aware of any movement to have him canonized, but from all accounts Fr. Hardon was a very holy man. I can't help but think he would intercede for further healing on behalf of Jeremy.
Posted by: Noah Nehm at May 24, 2006 8:17:36 PM
Reminds me of the wonderful Robin Williams movie "Awakening" about treating patients who had been years suffering with catatonia with el-dopa (sp.)
Cried my eyes out on that one.
Posted by: lw at May 24, 2006 11:58:45 PM
Whose idea was it to give sleep aids to the persistently vegetative?
The less charitable part of me wonders if there wasn't some hope that the subjects would just take the Big Sleep.
PVO
Posted by: mulopwepaul at May 25, 2006 4:11:51 PM



















